收费全文 | 83963篇 |
免费 | 7794篇 |
国内免费 | 2213篇 |
耳鼻咽喉 | 242篇 |
儿科学 | 1180篇 |
妇产科学 | 1253篇 |
基础医学 | 10439篇 |
口腔科学 | 2057篇 |
临床医学 | 8898篇 |
内科学 | 12249篇 |
皮肤病学 | 527篇 |
神经病学 | 8948篇 |
特种医学 | 2351篇 |
外国民族医学 | 2篇 |
外科学 | 7649篇 |
综合类 | 8537篇 |
现状与发展 | 6篇 |
一般理论 | 2篇 |
预防医学 | 11431篇 |
眼科学 | 882篇 |
药学 | 10293篇 |
58篇 | |
中国医学 | 4105篇 |
肿瘤学 | 2861篇 |
2024年 | 104篇 |
2023年 | 1426篇 |
2022年 | 1940篇 |
2021年 | 3607篇 |
2020年 | 4015篇 |
2019年 | 3155篇 |
2018年 | 3036篇 |
2017年 | 3363篇 |
2016年 | 3471篇 |
2015年 | 3410篇 |
2014年 | 6109篇 |
2013年 | 7238篇 |
2012年 | 5150篇 |
2011年 | 5759篇 |
2010年 | 4482篇 |
2009年 | 4522篇 |
2008年 | 4517篇 |
2007年 | 3977篇 |
2006年 | 3619篇 |
2005年 | 2842篇 |
2004年 | 2527篇 |
2003年 | 2266篇 |
2002年 | 1804篇 |
2001年 | 1513篇 |
2000年 | 1191篇 |
1999年 | 950篇 |
1998年 | 788篇 |
1997年 | 717篇 |
1996年 | 619篇 |
1995年 | 589篇 |
1994年 | 507篇 |
1993年 | 455篇 |
1992年 | 445篇 |
1991年 | 384篇 |
1990年 | 406篇 |
1989年 | 357篇 |
1988年 | 331篇 |
1987年 | 274篇 |
1986年 | 270篇 |
1985年 | 345篇 |
1984年 | 286篇 |
1983年 | 187篇 |
1982年 | 204篇 |
1981年 | 175篇 |
1980年 | 158篇 |
1979年 | 114篇 |
1978年 | 93篇 |
1977年 | 61篇 |
1976年 | 79篇 |
1975年 | 33篇 |
Methods: Forty-eight aMCI participants were randomized between a mindfulness-based intervention (MBI) and a psychoeducation-based intervention (PBI) for eight weekly sessions. Anxiety symptoms, perceived stress levels, cortisol awakening response (CAR), and coping strategies were assessed pre- and post-intervention. Mindfulness attitudes and time dedicated to at-home meditative practices were evaluated in the MBI group.
Results: The main results revealed a slight reduction of the CAR among MBI participants who practiced meditation at home the most and a decrease in perceived stress levels in the PBI group. Both interventions enhanced problem-focused coping strategies.
Conclusion: In sum, this pilot study supports the potential of MBI and PBI to reduce stress at the physiological and psychological level, respectively, and increase coping strategies in older adults at risk for AD. 相似文献
Objective: We examined characteristics of caregivers and stroke survivors associated with caregivers’ depressive symptoms in the early poststroke period.
Methods: We conducted a prospective, longitudinal exploratory observational study with a convenience sample of 63 caregivers of older adult (≥ 65 years) stroke survivors recruited from urban acute-care settings. We enrolled caregivers by 2 weeks poststroke (T1) and revisited them 4 weeks later (T2). Depressive symptoms were measured using the Patient Health Questionnaire-9. A separate unadjusted linear mixed model was computed to explore significant associations between each caregiver or stroke-survivor characteristic and depressive symptoms.
Results: Caregivers, on average, reported mild depressive symptoms at T1 and T2. Each of the following characteristics was independently associated with caregiver depressive symptoms over the first 6 weeks poststroke: caregiver uncertainty (p < 0.001), perceived stress (p < 0.001) but not cortisol levels (p = 0.858 on waking, p = 0.231 evening), coping (p < 0.001), social support (p = 0.006), race (p = 0.022), income (p = 0.001), time spent on care (p = 0.039), and stroke-survivor race (p = 0.033) and functional status (p = 0.003). At T2, caregiver depressive symptoms were correlated with evening cortisol level (p = 0.001).
Conclusions: Caregiver and stroke-survivor characteristics may help identify caregivers at highest risk for early depressive symptoms and guide interventions aimed at their resolution. 相似文献